DAD1 is required for the function and the structural integrity of the oligosaccharyltransferase complex.

doi:10.1074/jbc.273.40.26094

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Article

DAD1 is required for the function and the structural integrity of the oligosaccharyltransferase complex.

The Journal of biological chemistry - 2 Oct 1998

Sanjay A, Fu J, Kreibich G

Abstract excerpt

Asparagine-linked glycosylation is a highly conserved protein modification reaction that occurs in all eukaryotic organisms. The oligosaccharyltransferase (OST), which has its active site exposed on the luminal face of the endoplasmic reticulum (ER), catalyzes the transfer of preassembled high ma...

Topics

Animals
Apoptosis
Cell Line
Cricetinae
Endoplasmic Reticulum
Glycosylation
Hexosyltransferases
Membrane Proteins
Mutation
Temperature
Transferases

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