Article
Genetic analysis of Tp53 from urine sediment as a tool for diagnosing recurrence and residual of bladder carcinoma.
European urology - 1 Oct 2000
Sachs M D, Schlechte H, Lenk V S, Brenner S, Schnorr D, Fleige B, Ditscherlein G, Loening S A
Abstract excerpt
OBJECTIVES: Longitudinal study of Tp53 mutation in urine sediments of 26 patients with mutated primary transitional cell carcinoma (TCC) of the urinary bladder at different time periods after transurethral resection of the bladder (TURB), i.e. before and after the first TURB, prior to the control resection and before treatment of a recurrence. METHODS: DNA of the critical Tp53 exons 5-8 was anaylzed by...
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