Article
Functional studies of the BTB domain in the Drosophila GAGA and Mod(mdg4) proteins.
Nucleic acids research - 15 Oct 2000
Read D, Butte M J, Dernburg A F, Frasch M, Kornberg T B
Abstract excerpt
The BTB/POZ (BTB) domain is an approximately 120 residue sequence that is conserved at the N-terminus of many proteins in both vertebrates and invertebrates. We found that the protein encoded by a lethal allele of the Drosophila modifier of mdg4 [mod(mdg4)] gene has two mutated residues in its BTB domain. The identities of the residues at the positions of these mutations are highly conserved in the BTB domain...
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