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Article

A 3-dimensional model building by homology of the HFE protein: molecular consequences and application to antibody development.

Biochimica et biophysica acta - 29 Sept 2000

Dupradeau F, Altenberg-Greulich B, Warin R, Fuentes V, Monti J, Rochette J

Abstract excerpt

Genetic hemochromatosis (GH) is a common inherited disease of iron metabolism affecting 2-5 in 1000 individuals of European origin. A candidate gene for GH, namely HFE has been recently characterized. Structural studies of the protein product of the HFE gene are of major interest for a better understanding of the molecular physiopathology in iron overload. We have built a 3-dimensional model of the HFE protein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11018711
DOI: 10.1016/s0167-4838(00)00126-6

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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