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Article

Human haptoglobin structure and function--a molecular modelling study.

The FEBS journal - 1 Nov 2008

Polticelli F, Bocedi A, Minervini G, Ascenzi P

Abstract excerpt

Hemoglobin is the most prominent protein in blood, transporting O(2) and facilitating reactive oxygen and nitrogen species detoxification. Hemoglobin metabolism leads to the release of extra-erythrocytic hemoglobin, with potentially severe consequences for health. Extra-erythrocytic hemoglobin is complexed to haptoglobin for clearance by tissue macrophages. The human gene for haptoglobin consists of three...

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PMID: 18959750
DOI: 10.1111/j.1742-4658.2008.06690.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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