Article
Maternal cold inducible RNA binding protein is required for embryonic kidney formation in Xenopus laevis.
FEBS letters - 29 Sept 2000
Peng Y, Kok K H, Xu R H, Kwok K H, Tay D, Fung P C, Kung H F, Lin M C
Abstract excerpt
We cloned a major isoform of Xenopus homologue of cold inducible RNA binding protein (CIRP), XCIRP-1. XCIRP-1 was neither cold inducible nor essential for cell division during early embryonic development. Suppression of XCIRP-1 dose dependently produced tailbuds with deformations of the brain and internal organs. The defects were XCIRP-1 specific as they could be rescued by sense transcript. Suppression of...
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