Article
RNA interference for the organizer-specific gene Xlim-1 in Xenopus embryos.
Biochemical and biophysical research communications - 2 Aug 2000
Nakano H, Amemiya S, Shiokawa K, Taira M
Abstract excerpt
Double-stranded RNA (dsRNA) interferes with gene expression in various species, a phenomenon known as RNA interference (RNAi). We show here that RNAi is also effective in modifying gene expression in Xenopus embryos. First, expression of an exogenous luciferase gene as a reporter in embryos was reduced by coinjection with dsRNA corresponding to the luciferase gene. Next, injection of dsRNA for Xlim-1, a homeobox...
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