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Article

Regulation of the formation of tumor cell pseudopodia by the Na(+)/H(+) exchanger NHE1.

Journal of cell science - 1 Oct 2000

Lagana A, Vadnais J, Le P U, Nguyen T N, Laprade R, Nabi I R, Noël J

Abstract excerpt

The Na(+)/H(+) exchanger NHE1 is involved in intracellular pH homeostasis and cell volume regulation and accumulates with actin in the lamellipodia of fibroblasts. In order to determine the role of NHE1 following epithelial transformation and the acquisition of motile and invasive properties, we studied NHE1 expression in polarized MDCK cells, Moloney Sarcoma virus (MSV) transformed MDCK cells and an invasive...

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Identifiers

PMID: 11017880
DOI: 10.1242/jcs.113.20.3649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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