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Article

Angiotensin-Ⅱ and angiotensin-(1-7) imbalance affects comorbidity of depression and coronary heart disease.

Peptides - 1 Sept 2020

Han Wenxiu, Wei Zhijie, Dang Ruili, Guo Yujin, Zhang Hailiang, Geng Chunmei, Wang Changshui, Feng Qingyan, Jiang Pei

Abstract excerpt

A large body of evidence suggests a relationship between depression and coronary heart disease (CHD). Angiotensin-Ⅱ (Ang-Ⅱ) and angiotensin-(1-7) [Ang-(1-7)] are considered to exert biological effects in both conditions. Here, we aimed to determine the role of Ang-Ⅱ and Ang-(1-7) in the occurrence of comorbid depression in patients with CHD. Our study included 214 CHD patients and 100 matched healthy controls....

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Identifiers

PMID: 32599080
DOI: 10.1016/j.peptides.2020.170353

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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