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Article

Identification of genes specifically expressed in the accumulated visceral adipose tissue of OLETF rats

1 Oct 2000

Abstract excerpt

The Otsuka Long-Evans Tokushima fatty (OLETF) rat is an animal model of type 2 diabetes, characterized by abdominal obesity, insulin resistance, hypertension, and dyslipidemia. To elucidate the underlying molecular mechanism of obesity and its related complications, we used representational difference analysis and identified the genes more abundantly and specifically expressed in the visceral adipose tissue (VAT)...

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PMID: 11013303
DOI: 10.1016/s0022-2275(20)31994-5

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