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Article

High frequencies of telomeric associations, chromosome aberrations, and sister chromatid exchanges in ulcerative colitis.

The American journal of gastroenterology - 1 Sept 2000

Cottliar A, Fundia A, Boerr L, Sambuelli A, Negreira S, Gil A, Gómez J C, Chopita N, Bernedo A, Slavutsky I

Abstract excerpt

OBJECTIVE: Chromosome instability provides a predisposing background to malignancy, contributing to the crucial genetic changes in multistep carcinogenesis. The aim of this work was to analyze chromosome instability in patients with ulcerative colitis (UC) to achieve a better understanding of the increased risk for colorectal cancer. METHODS: Peripheral blood lymphocyte cultures from 20 untreated UC patients and...

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Identifiers

PMID: 11007232
DOI: 10.1111/j.1572-0241.2000.02315.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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