Article
Chromosome instability in lymphocytes from patients affected by or genetically predisposed to colorectal cancer.
Cancer genetics and cytogenetics - 1 Mar 1994
Richard F, Muleris M, Dutrillaux B
Abstract excerpt
To determine whether there are chromosomal clues to inherited forms of colorectal cancer, we studied chromosome instability in lymphocytes cultured from persons with sporadic colorectal cancer before treatment and from persons with a genetic predisposition to colorectal cancer due to adenomatous polyposis coli, Peutz-Jeghers syndrome, or juvenile polyposis. Spontaneous aberrations of chromosome number and...
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