Side-chain specificity at three temperature-sensitive folding mutation sites of P22 tailspike protein.

doi:10.1006/bbrc.1997.6566

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Article

Side-chain specificity at three temperature-sensitive folding mutation sites of P22 tailspike protein.

Biochemical and biophysical research communications - 28 Apr 1997

Lee S C, Yu M H

Abstract excerpt

The phage P22 tailspike protein is one of the few proteins for which both in vivo and in vitro folding pathways have been thoroughly characterized. Many temperature-sensitive folding (tsf) mutations that cause the mutant tailspike polypeptides not to be folded at high restrictive temperatures hav...

Topics

Bacteriophage P22
Glycoside Hydrolases
Models, Molecular
Mutagenesis, Site-Directed
Mutation
Protein Conformation
Protein Folding
Protein Structure, Secondary
Temperature
Viral Tail Proteins

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