Article
Mechanism for uptake of silica particles by monocytic U937 cells.
Human & experimental toxicology - 1 Jul 2000
Hetland G, Namork E, Schwarze P E, Aase A
Abstract excerpt
We examined the mechanism for uptake by monocytic cells of particles found in the atmosphere of some industrial work places. As a model system, irregular crystalline silica particles (SPs), sphere-like cryptocrystalline microsilica particles (MPs) and carbon particles (CPs) were exposed to pro-monocytic U937 cells. Plasma-treated SP and MP, but not CP, activated the alternative complement pathway, but bound...
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