DNA sequence variation in human apolipoprotein C4 gene and its effect on plasma lipid profile.

doi:10.1016/s0021-9150(99)00459-1

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Article

DNA sequence variation in human apolipoprotein C4 gene and its effect on plasma lipid profile.

Atherosclerosis - 1 Sept 2000

Kamboh M I, Aston C E, Hamman R F

Abstract excerpt

Human apolipoprotein C-IV (apoC-IV, protein; APOC4, gene) is a new member of the APO E/C1/C2 gene cluster. In transgenic mice, human apoC-IV is predominantly associated with very low-density lipoprotein (VLDL) and thus may play an important role in lipid metabolism. To our knowledge, the extent and nature of APOC4 genetic variation and its role in lipid metabolism are unknown. In this study we have assessed the...

Topics

Adult
Aged
Alleles
Apolipoproteins C
DNA
Female
Gene Frequency
Genetic Variation
Humans
Linear Models
Linkage Disequilibrium
Lipid Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lipids

Male

Middle Aged

Molecular Sequence Data

Polymerase Chain Reaction

Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 10996355
DOI: 10.1016/s0021-9150(99)00459-1

Genes

APOC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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