Article
Nonsynonymous polymorphic sites in the apolipoprotein (apo) A-IV gene are associated with changes in the concentration of apo B- and apo A-I-containing lipoproteins in a normal population.
American journal of human genetics - 1 May 1992
von Eckardstein A, Funke H, Schulte M, Erren M, Schulte H, Assmann G
Abstract excerpt
The aims of this study were to detect polymorphic sites in the apolipoprotein (apo) A-IV gene, to establish their frequencies, to determine potential haplotypes, and to investigate the role of these polymorphisms in lipid metabolism. A sequencing study of four individuals led to the identificatio...
Topics
- Adult
- Alleles
- Apolipoprotein A-I
- Apolipoproteins A
- Apolipoproteins B
- Base Sequence
- Endodeoxyribonucleases
- Genetic Linkage
- Genetic Variation
- Haplotypes
- Heterozygote
- Humans
- Molecular Sequence Data
- Polymorphism, Restriction Fragment Length