Molecular basis of a unique African variant (A-IV 5) of human apolipoprotein A-IV and its significance in lipid metabolism.

doi:10.1002/gepi.1370090602

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Article

Molecular basis of a unique African variant (A-IV 5) of human apolipoprotein A-IV and its significance in lipid metabolism.

Genetic epidemiology - 1 Jan 1992

Kamboh M I, Williams E R, Law J C, Aston C E, Bunker C H, Ferrell R E, Pollitzer W S

Abstract excerpt

Human apolipoprotein A-IV (apoA-IV) exhibits a genetically determined structural polymorphism amenable to analysis by isoelectric focusing and immunoblotting techniques. We have determined the allele frequency and molecular basis of a unique ApoA-IV*5 allele which is widely distributed among blacks but is absent in other populations. The frequency of the ApoA-IV*5 allele in blacks (N = 308) was estimated to be...

Topics

Adolescent
Adult
Alleles
Amino Acid Sequence
Apolipoproteins A
Base Sequence
Black People
DNA
Female
Humans
Lipid Metabolism
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Phenotype

Polymerase Chain Reaction

Polymorphism, Genetic

South Carolina

Source

Open in PubMed

Identifiers

PMID: 1487136
DOI: 10.1002/gepi.1370090602

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1487136-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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