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Article

Solution structure of a mutant of transcription factor 1: implications for enhanced DNA binding.

Journal of molecular biology - 29 Sept 2000

Liu W, Vu H M, Geiduschek E P, Kearns D R

Abstract excerpt

An NMR solution structure of a mutant of the homodimer protein transcription factor 1, TF1-G15/I32 (22 kDa), has been solved to atomic resolution, with 23 final structures that converge to an r.m. s.d. of 0.78 A. The overall shape of TF1-G15/I32 remains similar to that of the wild-type protein and other type II DNA-binding proteins. Each monomer has two N-terminal alpha-helices separated by a short loop, followed...

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PMID: 10993726
DOI: 10.1006/jmbi.2000.4084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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