Article
MCP-1 and CCR2 gene polymorphisms in Czech patients with allergic disorders.
International journal of immunogenetics - 1 Feb 2009
Holla L Izakovicova, Mrazek F, Petrek M
Abstract excerpt
Several lines of evidence suggest that chemokines play an important role in asthma and allergy. We analysed polymorphisms at -2518A/G and -2076A/T of MCP-1 and V64I of CCR2 gene in healthy subjects (n = 306) and allergic patients (n = 332). Allele and genotype frequencies did not differ significantly between groups. Nevertheless, MCP-1 variants were associated with allergen sensitization. The results suggest that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
