Article
Natural killer cells and mast cells from gp49B null mutant mice are functional.
Molecular and cellular biology - 1 Oct 2000
Rojo S, Stebbins C C, Peterson M E, Dombrowicz D, Wagtmann N, Long E O
Abstract excerpt
Immune responses are controlled by a combination of positive and negative cellular signals. Effector cells in the immune system express inhibitory receptors that serve to limit effector cell expansion and to protect the host from autoreactivity. gp49B is a receptor of unknown function that is expressed on activated mast cells and natural killer (NK) cells and whose cytoplasmic tail endows it with inhibitory...
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