Article
BUR1 and BUR2 encode a divergent cyclin-dependent kinase-cyclin complex important for transcription in vivo.
Molecular and cellular biology - 1 Oct 2000
Yao S, Neiman A, Prelich G
Abstract excerpt
BUR1 and BUR2 were previously identified by a genetic selection for mutations that increase transcription from basal promoters in vivo. BUR1 encoded a putative protein kinase with greatest similarity to members of the cyclin-dependent kinase (CDK) family, although that similarity was not sufficient to classify it as a CDK. It was also not known whether Bur1 activity was cyclin dependent and, if so, which cyclins...
Topics
- Alleles
- Amino Acid Sequence
- Candida albicans
- Cell Cycle
- Cloning, Molecular
- Cyclin-Dependent Kinases
- Cyclins
- Fungal Proteins
- Gene Deletion
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Molecular Sequence Data
- Phenotype
- Phosphorylation