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Article

RNase L-Independent Specific 28S rRNA Cleavage in Murine Coronavirus-Infected Cells

1 Oct 2000

Abstract excerpt

We characterized a novel 28S rRNA cleavage in cells infected with the murine coronavirus mouse hepatitis virus (MHV). The 28S rRNA cleavage occurred as early as 4 h postinfection (p.i.) in MHV-infected DBT cells, with the appearance of subsequent cleavage products and a decrease in the amount of intact 28S rRNA with increasing times of infection; almost all of the intact 28S rRNA disappeared by 24 h p.i. In...

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PMID: 10982321
DOI: 10.1128/jvi.74.19.8793-8802.2000

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