Article
The influence of HLA genotyping compatibility on clinical outcome after cord blood transplantation from unrelated donors.
Journal of hematotherapy & stem cell research - 1 Aug 2000
Ohnuma K, Isoyama K, Ikuta K, Toyoda Y, Nakamura J, Nakajima F, Nishihira H
Abstract excerpt
We performed retrospective DNA typing of class I (A, B, Cw) and class II (DRB1, DQB1, DPB1) HLA alleles in 27 unrelated cord blood transplantation (CBT) cases donated from a single cord blood bank (Kanagawa Cord Blood Bank). The influence of HLA genotype matching on clinical outcome was evaluated. From Cox's model, we found that incompatibility of two or more HLA alleles between the donor and recipient of an...
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