Article
Predictions of gene family distributions in microbial genomes: evolution by gene duplication and modification.
Physical review letters - 18 Sept 2000
Yanai I, Camacho C J, DeLisi C
Abstract excerpt
A universal property of microbial genomes is the considerable fraction of genes that are homologous to other genes within the same genome. The process by which these homologues are generated is not well understood, but sequence analysis of 20 microbial genomes unveils a recurrent distribution of gene family sizes. We show that a simple evolutionary model based on random gene duplication and point mutations fully...
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