Article
Association of angiotensin I converting enzyme gene polymorphism with reflux nephropathy in children.
Nephron - 1 Sept 2000
Park H W, Koo J W, Kim J S, Ha I S, Cheong H I, Choi Y
Abstract excerpt
Deletion polymorphism of angiotensin I converting enzyme (ACE) gene has been studied as a risk factor in various cardiovascular diseases and chronic nephropathies. Perturbation of local and systemic renin-angiotensin systems is one of the possible mechanisms of the progression of reflux nephropathy. In this study, the implication of ACE gene polymorphism in renal scarring and deterioration of renal function was...
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