Article
ACE gene polymorphism and renal scarring in primary vesicoureteric reflux.
Pediatric nephrology (Berlin, Germany) - 1 Dec 2002
Haszon Ibolya, Friedman Aaron L, Papp Ferenc, Bereczki Csaba, Baji Sándor, Bodrogi Tibor, Károly Eva, Endreffy Emöke, Túri Sándor
Abstract excerpt
The objective of this study was to investigate whether mutations of the renin-angiotensin system genes are involved in primary vesicoureteric reflux (VUR) and VUR-associated renal scarring. The M235T polymorphism of the angiotensinogen ( ATG) gene, the I/D polymorphism of the angiotensin converting enzyme ( ACE) gene, and the A1166C polymorphism of the angiotensin II type 1 receptor ( AT1) gene were identified in...
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