Article
Identification of novel common polymorphisms in the promoter region of the TIMP-3 gene in Czech population.
Molecular and cellular probes - 1 Aug 2000
Beránek M, Kanková K, Muzík J
Abstract excerpt
We investigated possible polymorphisms in the promoter regions of the TIMP-1, 2 and 3 genes (tissue inhibitor of metalloproteinases) to establish their frequencies in the Caucasian population. Polymorphisms were analysed by means of heteroduplex analysis and fragments with altered mobility were sequenced. No polymorphisms were found in the promoters for TIMP-1 and 2 but three novel polymorphisms (-899T/A, -915A/G...
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