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Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney

1 Sept 2000

Abstract excerpt

We examined in this study the expression of the potential-sensitive organic cation transporter OCT3 in the kidney. A functionally active OCT3 was cloned from a mouse kidney cDNA library. The cloned transporter was found to be capable of mediating potential-dependent transport of a variety of organic cations including tetraethylammonium. This function was confirmed in two different heterologous expression systems...

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PMID: 10966924
DOI: 10.1152/ajprenal.2000.279.3.f449

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