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Article

Suppressors of translation initiation defect in hem12 locus of Saccharomyces cerevisiae.

Acta biochimica Polonica - 1 Jan 2000

Góra M, Pluta K, Chelstowska A, Zoładek T

Abstract excerpt

A system for the positive selection of transational initiation suppressors in S. cerevisiae has been developed. A mutant with an ATA initiation codon in the HEM12 gene, encoding uroporphyrinogen decarboxylase, was used to select cis- and trans-acting suppressors. These suppressors partially restore growth on nonfermentable carbon sources, such as glycerol, but still allow the accumulation of porphyrins. All...

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PMID: 10961692

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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