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Article

Ventilatory responses to acute and chronic hypoxia in mice: effects of dopamine D(2) receptors.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Sept 2000

Huey K A, Low M J, Kelly M A, Juarez R, Szewczak J M, Powell F L

Abstract excerpt

We used genetically engineered D(2) receptor-deficient [D(2)-(-/-)] and wild-type [D(2)-(+/+)] mice to test the hypothesis that dopamine D(2) receptors modulate the ventilatory response to acute hypoxia [hypoxic ventilatory response (HVR)] and hypercapnia [hypercapnic ventilatory response (HCVR)] and time-dependent changes in ventilation during chronic hypoxia. HVR was independent of gender in D(2)-(+/+) mice and...

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Source

Identifiers

PMID: 10956362
DOI: 10.1152/jappl.2000.89.3.1142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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