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Article

Protein Synthesis Shut-Off Induced by Influenza Virus Infection Is Independent of PKR Activity

15 Sept 2000

Abstract excerpt

The role of PKR activity in influenza virus-induced cell shut-off was studied by infection of PKR(+) or PKR(-) cell cultures and metabolic labeling in vivo. No differences in the synthesis of viral proteins or the decay of cellular protein synthesis were observed. To investigate the relevance of the inhibition of cellular pre-mRNA polyadenylation and nucleocytoplasmic transport in virus-induced shut-off, we...

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PMID: 10954584
DOI: 10.1128/jvi.74.18.8781-8784.2000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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