Article
Class II MHC antigens in early rheumatoid arthritis in Bath (UK) and Madrid (Spain).
Rheumatology (Oxford, England) - 1 Aug 2000
Balsa A, Minaur N J, Pascual-Salcedo D, McCabe C, Balas A, Fiddament B, Vicario J L, Cox N L, Martín-Mola E, Hall N D
Abstract excerpt
OBJECTIVE: A number of studies have indicated that rheumatoid arthritis (RA) is a less severe disease in Mediterranean countries than in Northern Europe. We investigated whether differences in the frequency of class II MHC antigens might contribute to this variation in disease severity. METHODS: Typing at HLA-DR and -DQ loci was carried out at low and high resolutions by polymerase chain reaction amplification in...
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