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Article

Activation of cellular interferon-responsive genes after infection of human cells with herpes simplex virus type 1

1 Sept 2000

Abstract excerpt

Previous studies have shown that infection of human fibroblasts with human cytomegalovirus (HCMV) results in activation of cellular interferon-responsive gene expression. We demonstrate here that infection of human fibroblasts with herpes simplex virus type 1 (HSV-1) in the absence of de novo protein synthesis also induces the expression of interferon-responsive genes. Five genes tested (encoding ISG54, IFI56,...

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PMID: 10950979
DOI: 10.1099/0022-1317-81-9-2215

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