Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human influenza viruses activate an interferon-independent transcription of cellular antiviral genes: Outcome with influenza A virus is unique

11 Jul 2002

Abstract excerpt

We examine the IFN-alpha/beta-independent activation of cellular transcription that constitutes an early antiviral response of cells against influenza A and B viruses, which cause widespread epidemics in humans. We show that influenza B virus induces the synthesis in human cells of several mature mRNAs encoded by genes containing an IFN-alpha/beta-stimulated response element (ISRE). Consequently, the IFN...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Immune Response and Inflammation
Share to interferon and immune responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12114540
DOI: 10.1073/pnas.152327499

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human influenza viruses activate an interferon-independent transcription of cellular antiviral genes: Outcome with influenza A virus is uniquePMID 12114540Read ↗

Incoming influenza A virus evades early host recognition, while influenza B virus induces interferon expression directly upon entry.Semantic proximity Read ↗

Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein.Semantic proximity Read ↗

The role of differential expression of human interferon-A genes in antiviral immunitySemantic proximity Read ↗

Multiple Anti-Interferon Actions of the Influenza A Virus NS1 ProteinSemantic proximity Read ↗

Host Cell Restriction Factors that Limit Influenza A InfectionSemantic proximity Read ↗

Multiple Viral microRNAs Regulate Interferon Release and Signaling Early during Infection with Epstein-Barr VirusSemantic proximity Read ↗

Sendai Virus Infection Induces Expression of Novel RNAs in Human CellsSemantic proximity Read ↗

Influenza A virus strains that circulate in humans differ in the ability of their NS1 proteins to block the activation of IRF3 and interferon-β transcriptionSemantic proximity Read ↗

Group 2 coronaviruses prevent immediate early interferon induction by protection of viral RNA from host cell recognitionSemantic proximity Read ↗

Rapid Decay of Host Basal mRNAs During SARS-CoV-2 Infection Perturbs Host Antiviral mRNA Biogenesis and ExportSemantic proximity Read ↗

Post-Transcriptional Regulation of Interferons and Their Signaling PathwaysSemantic proximity Read ↗

Essential role of hsa-miR-203a-3p in type I Interferons immune homeostasis during Influenza and NDV infectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.