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Article

Thrombotic dysfibrinogenemia. Fibrinogen "Caracas V" relation between very tight fibrin network and defective clot degradability.

Thrombosis research - 15 Jul 2000

Marchi R, Mirshahi S S, Soria C, Mirshahi M, Zohar M, Collet J P, de Bosch N B, Arocha-Piñango C L, Soria J

Abstract excerpt

Fibrinogen Caracas V is a thrombotic dysfibrinogenemia with an Aalpha 532 Ser-->Cys mutation characterized by a tight fibrin network formed of thin fibers responsible for a less porous clot than a normal one. In the present work, fibrinogen Caracas V is further characterized in order to understand the relationship between the structural defect and thrombophilia. This thrombotic disorder has been attributed to a...

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PMID: 10946093
DOI: 10.1016/s0049-3848(00)00235-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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