Article
Coexisting dysfibrinogenemia (gammaR275C) and factor V Leiden deficiency associated with thromboembolic disease (fibrinogen Cedar Rapids).
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Apr 2000
Siebenlist K R, Mosesson M W, Meh D A, DiOrio J P, Albrecht R M, Olson J D
Abstract excerpt
Fibrinogen Cedar Rapids is a heterozygous dysfibrinogenemia (gammaR275C) that was associated with thromboembolism during and following pregnancy in three second-generation family members who also were heterozygotic for factor V Leiden (V R506Q). Like other dysfibrinogenemias with substitutions at position 275 of the gamma-chain, fibrinogen Cedar Rapids is characterized by defective end-to-end intermolecular...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
