Article
MAOA methylation is associated with impulsive and antisocial behaviour: dependence on allelic variation, family environment and diet.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2024
Kanarik Margus, Sakala Katre, Matrov Denis, Kaart Tanel, Roy Arunima, Ziegler Georg C, Veidebaum Toomas, Lesch Klaus-Peter, Harro Jaanus
Abstract excerpt
Congenital absence of monoamine oxidase A (MAO-A) activity predisposes to antisocial impulsive behaviour, and the MAOA uVNTR low-expressing genotype (MAOA-L) together with childhood maltreatment is associated with similar phenotypes in males. A possible explanation of how family environment may lead to such behaviour involves DNA methylation. We have assessed MAOA methylation and impulsive/antisocial behaviour in...
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