Article
Salicylate induction of phenotypic resistance to quinolones in Serratia marcescens.
The Journal of antimicrobial chemotherapy - 1 Aug 2000
Berlanga M, Viñas M
Abstract excerpt
The influence of salicylic acid on the permeability and susceptibility of Serratia marcescens to both nalidixic acid and ciprofloxacin was studied, as well as the effect of salicylate on outer membrane proteins and lipopolysaccharide. As salicylic acid concentration increased, ciprofloxacin accumulation decreased with a concomitant, previously observed, reduction in the porin content of the outer membrane....
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