Article
Transient carbapenem resistance induced by salicylate in Pseudomonas aeruginosa associated with suppression of outer membrane protein D2 synthesis.
Antimicrobial agents and chemotherapy - 1 Dec 1993
Sumita Y, Fukasawa M
Abstract excerpt
Pseudomonas aeruginosa PAO1 showed increased phenotypic resistance to imipenem, panipenem, and biapenem specifically in the presence of salicylate. The antipseudomonal activity of carbapenems was reduced in proportion to the concentration of salicylate. This resistance was transient and nonherita...
Topics
- Anti-Arrhythmia Agents
- Anti-Bacterial Agents
- Bacterial Outer Membrane Proteins
- Carbapenems
- Drug Resistance, Microbial
- Microbial Sensitivity Tests
- Phenotype
- Pseudomonas aeruginosa
- Salicylates
- Salicylic Acid