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Article

Lewis antigens in Helicobacter pylori: biosynthesis and phase variation

1 Jun 2000

Abstract excerpt

The lipopolysaccharides (LPS) of most Helicobacter pylori strains contain complex carbohydrates known as Lewis antigens that are structurally related to the human blood group antigens. Investigations on the genetic determinants involved in the biosynthesis of Lewis antigens have led to the identification of the fucosyltransferases of H. pylori, which have substrate specificities distinct from the mammalian...

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PMID: 10931272
DOI: 10.1046/j.1365-2958.2000.01934.x

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