Article
Familial isolated hyperparathyroidism maps to the hyperparathyroidism-jaw tumor locus in 1q21-q32 in a subset of families.
The Journal of clinical endocrinology and metabolism - 1 Jun 1998
Teh B T, Farnebo F, Twigg S, Höög A, Kytölä S, Korpi-Hyövälti E, Wong F K, Nordenström J, Grimelius L, Sandelin K, Robinson B, Farnebo L O, Larsson C
Abstract excerpt
Approximately 70 families with familial isolated hyperparathyroidism (FIHP) have been reported. Whether it is a separate entity or a variant of multiple endocrine neoplasia type 1 (MEN1 at 11q13) or hyperparathyroidism-jaw tumor (HPT-JT or HRPT2 at 1q21-32) syndrome is not known. We describe here...
Topics
- Adult
- Alleles
- Chromosome Mapping
- Chromosomes, Human, Pair 1
- Female
- Haplotypes
- Humans
- Hyperparathyroidism
- Lod Score
- Loss of Heterozygosity
- Male
- Parathyroid Glands
- Parathyroid Neoplasms
- Pedigree