Article
Molecular characterization of the key switch F provides a basis for understanding the rapid divergence of the sex-determining pathway in the housefly.
Genetics - 1 Jan 2010
Hediger Monika, Henggeler Caroline, Meier Nicole, Perez Regina, Saccone Giuseppe, Bopp Daniel
Abstract excerpt
The housefly, Musca domestica, is an excellent model system to study the diversification of the pathway that specifies the sexual fate. A number of different mechanisms have been described in the housefly, which reflects in part the broad diversity of sex-determining strategies used in insects. In this study we present the molecular identification and characterization of F, which acts as the master switch in the...
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