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Comprehensive analysis of karyotypic mosaicism between trophectoderm and inner cell mass

19 Jul 2010

Abstract excerpt

Aneuploidy has been well-documented in blastocyst embryos, but prior studies have been limited in scale and/or lack mechanistic data. We previously reported preclinical validation of microarray 24-chromosome preimplantation genetic screening in a 24-h protocol. The method diagnoses chromosome copy number, structural chromosome aberrations, parental source of aneuploidy and distinguishes certain meiotic from...

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PMID: 20643877
DOI: 10.1093/molehr/gaq062

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