Article
Identification of an export control sequence and a requirement for the KH domains in ICP27 from herpes simplex virus type 1.
Journal of virology - 1 Aug 2000
Soliman T M, Silverstein S J
Abstract excerpt
The herpes simplex virus type 1 (HSV-1) immediate-early protein ICP27 is an RNA-binding protein that performs multiple functions required for the expression of HSV-1 genes during a productive infection. One essential function involves shuttling between the nucleus and the cytoplasm. Some of the domains identified in ICP27 include a leucine-rich nuclear export sequence (NES), a nuclear localization signal, three...
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