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Article

PTEN, a unique tumor suppressor gene.

Endocrine-related cancer - 1 Jun 2000

Dahia P L

Abstract excerpt

For many years, it has been thought that the chromosome region 10q22-24 includes one or more genes that appear to play a role in several human malignancies. PTEN is a new tumor suppressor gene encoding a dual-specificity phosphatase that was cloned simultaneously by three groups (Li & Sun 1997, Li et al. 1997, Steck et al. 1997), two of which used a positional cloning approach to identify genes in chromosome 10...

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Share to Phosphoric Monoester Hydrolases
Share to PTEN Phosphohydrolase
Share to Tumor Suppressor Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apoptosis

Share to Chromosomes, Human, Pair 10

Share to Cloning, Molecular

Share to Genes, Tumor Suppressor

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Source

Identifiers

PMID: 10903528
DOI: 10.1677/erc.0.0070115

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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