Transient antiislet autoantibodies: infrequent occurrence and lack of association with "genetic" risk factors.

doi:10.1210/jcem.85.7.6670

Article

Transient antiislet autoantibodies: infrequent occurrence and lack of association with "genetic" risk factors.

The Journal of clinical endocrinology and metabolism - 1 Jul 2000

Yu J, Yu L, Bugawan T L, Erlich H A, Barriga K, Hoffman M, Rewers M, Eisenbarth G S

Abstract excerpt

We hypothesized that genetic determinants of expression of persistent antiislet autoantibodies would similarly influence the expression of transient autoantibodies. To test this hypothesis, we prospectively evaluated sera from 478 relatives (SOC: sibling-offspring cohort) of patients with type 1 diabetes as well as 793 newborns from the general population (NEC: newborn nonrelative cohort) selected for expression...

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Transient antiislet autoantibodies: infrequent occurrence and lack of association with "genetic" risk factors.

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