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Article

Altered calcium homeostasis in cerebellar Purkinje cells of leaner mutant mice.

Journal of neurophysiology - 1 Jul 2000

Dove L S, Nahm S S, Murchison D, Abbott L C, Griffith W H

Abstract excerpt

The leaner (tg(la)) mouse mutation occurs in the gene encoding the voltage-activated Ca(2+) channel alpha(1A) subunit, the pore-forming subunit of P/Q-type Ca(2+) channels. This mutation results in dramatic reductions in P-type Ca(2+) channel function in cerebellar Purkinje neurons of tg(la)/tg(l...

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Identifiers

PMID: 10899223
DOI: 10.1152/jn.2000.84.1.513

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10899223-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Altered calcium homeostasis in cerebellar Purkinje cells of leaner mutant mice.PMID 10899223Read ↗

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