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Article

Age- and sex-distribution of the mutation load.

Genetica - 1 Jan 1999

Hansen T F, Price D K

Abstract excerpt

We investigate the age and sex distribution of genetic fitness under mutation-selection balance by means of simple one-locus two-allele models. We find that the extent of age and sex variation in the mutation load is very dependent on the average effect of new mutations. If the average heterozygote selective effect of new mutations is large, then age and sex differences may constitute a significant fraction of...

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Identifiers

PMID: 10897798
DOI: 10.1023/a:1003988101586

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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