Article
Theoretical models of selection and mutation on quantitative traits.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Jul 2005
Johnson Toby, Barton Nick
Abstract excerpt
Empirical studies of quantitative genetic variation have revealed robust patterns that are observed both across traits and across species. However, these patterns have no compelling explanation, and some of the observations even appear to be mutually incompatible. We review and extend a major class of theoretical models, 'mutation-selection models', that have been proposed to explain quantitative genetic...
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