Article
Deleterious mutations and the evolution of sex.
Science (New York, N.Y.) - 13 Oct 2000
Keightley P D, Eyre-Walker A
Abstract excerpt
It has been suggested that sexual reproduction is maintained because it reduces the load imposed by recurrent deleterious mutations. If rates of deleterious mutation per diploid genome per generation (U) exceed 1, and mutations interact synergistically, then sexuals can overcome their inherent twofold disadvantage. We have tested this hypothesis by estimating genomic point mutation rates for protein-coding genes...
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